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Databases Programming Software Biotech IT Science

Technology Vs. E.coli Outbreaks 45

jcatcw writes "The Centers for Disease Control and Prevention (CDC) found the patterns of illness in both of the recent E. coli outbreaks — packaged spinach and Taco Bell — using PulseNet, which uses a customized version of BioNumerics to conduct comparisons and analysis of samples in a SQL Server database. PulseNet holds the DNA fingerprints provided by pulsed field gel electrophoresis (PFGE). It operates at a national level and can link small, localized cases in a nationwide pattern. 'We can now see the connections you would not have seen before, which has revolutionized the world of food safety,' according to John Besser, clinical laboratory manager at the Minnesota Department of Health and a member of the Association of Public Health Laboratories."
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Technology Vs. E.coli Outbreaks

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  • If people are still getting sick.
    • Re: (Score:2, Funny)

      by McGiraf ( 196030 )
      yeh, but now they can look at nice geo-distibution graphics while they are hospitalized.
    • by sporkme ( 983186 ) * on Sunday December 31, 2006 @02:09PM (#17416960) Homepage
      The point is that individual cases and the associated behaviors can be aligned and collated to trace the source of an outbreak. It is revolutionary in that many fewer people are getting sick.

      There is no way to stop the spread of a disease directly with a database, but this system was fast and accurate enough to track down the source before the outbreak became something more like an epidemic. Taco Bell is so popular that this could have added up to hundreds of thousands of cases before someone realized the source.
      • Granted, but I was referring to the fact that it's not revolutionary enough, since Taco Bell is still around. ;)
        • Re: (Score:3, Funny)

          Comment removed based on user account deletion
        • How would us Americans maintain our fat asses without Taco Bell and the mega transfat combo value menu?

          Come to think of it, maybe an outbreak of serious illness every once in a while would be a good thing... horrible diarrhea is a very aggressive weight loss program.

          Ok, back to my heart-attack-in-a-sack.
          • Re: (Score:3, Insightful)

            by cyberworm ( 710231 )
            You have obviously not eaten at taco bell very often. Horrible diarrhea comes even without the food poisoning.
  • by Spazntwich ( 208070 ) on Sunday December 31, 2006 @01:48PM (#17416820)
    Seems it would take a while for the DNA to grow enough to supply fingerprints.
    • DNA replicates pretty quickly. What would be cool is if one day in the future, everyone who goes to the doctor to get treated for a virus then gets the virus quickly fingerprinted, so that way the pattern of spread of the virus among the population can be monitored.
      • Patient: Doctor, I am not feeling so well.
        Doc: You got terribliomax contagiatitis, a very contagious disease. We have quarantine everyone you had contact with. Did you have contact with anyone?
        Patient: I shook hands with your receptionist.
        Doc: She will get it.
        Patient: Before that I bought a newspaper and gave the boy some cash.
        Doc: He will get it too.

        [snip out the long story and cutting to the chase]

        Patient: Before that I kissed my wife before leaving for work.
        Doc: Shit! I am going to get it too.

        This is wha
    • actually no since the DNA has chunks that can be read (think source code type fingerprints structure of modules type of indenting choice of variable names)
    • by shawb ( 16347 ) on Sunday December 31, 2006 @02:20PM (#17417010)
      You really don't have to grow a culture of the bacteria. Polymerase Chain Reaction [wikipedia.org] and other techniques can replicate DNA rapidly enough to make amounts suitable for laboratory testing in a practically negligible time.
  • Great! (Score:2, Funny)

    by e.colli ( 630500 )
    They will do an plugin for Google Earth?
  • by gvc ( 167165 ) on Sunday December 31, 2006 @02:09PM (#17416956)
    E. Coli is an essential part of our (and animals') digestive process. Most strains of E. Coli are harmless to humans, but some, like O157:H7 are extremely virulent in humans but harmless to the animals that carry them.

    It makes sense to spend our efforts trying to eradicate these strains in the domestic and wild animal populations. Otherwise, we run the risk of every farmer's field and every outdoor trail becoming a serious health hazard.

    So while the epidemiologic effort to trace the source of the human outbreak is impressive, I think research into controlling it in animals [ufl.edu] is even more important.

    • Or we could not feed cows so much corn that they end up having stomachs of pH 3. If cattle had stomach pH they evolved to have E. Coli would die in our stomachs. There is published paper [fass.org] that says this.
      • I wish I had mod points. There are beef companies trying to do it right. Look for "range fed" or "grass fed" beef [google.com]. Here are things to look for in a beef supplier (or rather verify that they *don't* do them):
        1. Non-therapuetic antibiotics used as growth enhancers - increases risk of antibiotic resistent pathogens for everyone, not just beef eaters.
        2. Feed "enhanced" with rendered carcases (cannabalistic cows) - causes mad cow disease. Outlawed most places, but feed companies can cheat or make mistakes [mindfully.org].
        3. C
      • by GWBasic ( 900357 )

        Grass is too expensive, just give the cows Tums!

        On a more serious note, after reading The Omnivore's Dillemma [amazon.com], I started buying grass-fed meat at Whole Foods. Personally, I find the beef tough; but the pork is to die for!

    • by Raptoer ( 984438 )
      While simply wiping out every microbe that might be a threat sounds like a great idea, this could backfire. If a person isn't exposed to microbes, especially while young, it leaves the person more susceptible to other microbes that come along. I agree that some have to be wiped out (smallpox, flu of 1918, and most likely these strains of E. Coli), however we must be careful with how far it goes. Also these do act as a population control function, but that isn't really an issue in the modern world. If we REA
  • Seriously, while mildly interesting, I don't think that business intelligence software is front-page-worthy.
  • by buckinflazed ( 1045374 ) on Sunday December 31, 2006 @02:38PM (#17417094)
    A guy on tv said,"Who is shitting in the spinach!". The other guy said, "No one is shitting on the spinach, it is the fertilizer that is the source of the outbreak". To which the man replied, "O.K., Who's shitting in the fertilizer!". I laughed my ass off
  • Tech Wonders! (Score:3, Interesting)

    by twitter ( 104583 ) on Sunday December 31, 2006 @03:15PM (#17417350) Homepage Journal

    The database is nice but it would be nicer if we'd simply apply what we already know to prevent the outbreaks in the first place. There's nothing new about composting and how to do it safely, yet we see big commercial farms rush the job and spray immature and dissease causing crap on food stuffs that will be eaten raw. I'm not sure if this is a problem of economies of scale or lax enforcement of existing laws. I am sure that the problem needs to be fixed in a way that won't discriminate against small operators who have never had the problem to begin with.

  • is food irradiation.

    You don't need complex insights into the food chain and fast reaction time, if you kill the E. Coli, Salmonella, Listeria and Shigella at the source. Most likely any contamination would be from food preparation at home or in a restaurant.
    • The problem with irradiation of veggies & fruits is the high-energy radition tends to ruin the flavor and/or flesh of the food good.
  • typo (Score:3, Funny)

    by j00r0m4nc3r ( 959816 ) on Sunday December 31, 2006 @04:01PM (#17417606)
    revolutionized the world of food safety

    I think what he meant to say was, "the EXCITING world of food safety"
  • by jmichaelg ( 148257 ) on Sunday December 31, 2006 @04:50PM (#17417916) Journal
    The spinach contamination a few months ago was traced to a field about 30 miles from where I live. The speculation is that some wild pigs (boars) were snacking on some spinach in the field and and an infected pig took a dump. It's probably not the first time this has happened, nor will it be the last. Shit happens.

    I think a bigger problem is how so much clean spinach was destroyed as a result. The pig probably ruined a few heads of spinach. Those few heads got mixed in with a bunch of clean spinach as the spinach was pre-packaged. So that one pig's dump killed more people than would have died a few years ago if they had eaten head spinach. We could irradiate the packaged produce to clean the spinach further than its current 3 wash cycle but some people won't eat irradiated food. Even still, there's probably a variety of bug out there that would survive x-raying. If you eat spinach from a head of spinach, you run the risk of not cleaning it sufficiently as well as dealing with the multiple number of hands that have touched it between the field and your mouth. Never mind intentional contamination like the Tylenol killer came up with or the zealots in Oregon who contaminated a salad bar so voter turnout would be low.

    In short, there's no way to guarantee that every piece of food that goes into your mouth is benign. With techniques such as the one described in the article, we'll hear of more people dying from contaminated food than we otherwise would have. People will panic, food will be destroyed, lawyers will sue and we'll plod along eating slightly more expensive food as a result. Will we be any better off? Probably not.

    In fact, we may be worse off. As people demand more safety, government power will grow. We won't be safer, but the government will be larger which means we'll all be the poorer.
     
  • If our FDA had not reduced so many inspectors -- perhaps this would never have become an "outbreak." At the very least the "Penny wise, Pound foolish" nature of our current Administration has almost allowed the Spinach industry to be ruined.

    10 years ago, would it have taken a month to find the "source?" I remember little outbreaks like this in the past, and by the next day, we'd know what to avoid. We just heard "don't eat spinach." So, every salad bar, every grocery store, every restaurant dumped tons of s
  • 'We can now see the connections you would not have seen before, which has revolutionized the world of food safety,'

    Excuse me but, you've not revolutionized food safety until you can prevent these outbreaks. So far you're still operating in 20/20 hindsight mode of "Now we know what happened."

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