ColdFusion Programming Methodologies?

lars-o-matic asks: "I work at a small (dozen people) company doing quite well building small-to-medium sized sites on the ColdFusion platform and the Fusebox architecture (which also has PHP and JSP versions). With our growth, increasing demand for Flash apps, new features of CFMX, and wanting to take on larger projects, we are researching methodologies. We like Fusebox3 for CF but worry it does not leverage the new object-like CF Components, web services, Flash remoting etc. and wonder if some kind of model-view-controller approach would help separate presentation from business logic. And there's structured documentation, re-usability, maintenance and yes, performance to consider. We're happy with the platform, which suits our project scale. We're not (yet) building a Google or an Amazon.com. It's methodology we need. How have the Slashdot CF users out there scaled from 2 to several coders and from little sites to larger ones?"